PT590. Behavioral and psychological symptoms of dementia and antipsychotic drug use in the elderly with dementia in Korea long-term care facilities

2016 International Journal of Neuropsychopharmacology  
Abstracts | 17 that only the years of education(β = -.38, p = .02) was significant to predict CS difference(adjusted R2 = .12, F(1, 37) = 6.27, p = .02). In the gray matter thickness analysis, thinner precuneus, cuneus and posterior cingulate gyrus predicted memory improvement(CS difference (p <0.05 RFT corrected)).; beta =-.37, t =4.16, number of vertex =231, Peak MNI coordinate(x, y, z) =(4.90, -68.97, 29.38). In DTI analysis, FA and RD of splenium corpus callosum were significantly
more » ... with CS difference after FWE correction (p < .005); r =.35, p =.03 for FA; r =-.35, p =.03 for RD. Initial neuropsychological traits and brain morphology could be a promising method to predict cognitive enhancement after training. Poor strategies in memory and higher integrity of hippocampal network may be closely associated with outcomes of multi-strategic training based on metamemory concept.
doi:10.1093/ijnp/pyw044.590 fatcat:5harun7ijrhoxcrrlvtknudp2y