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Effect of charred Radix et Rhizoma Rhei in a laser-induced choroidal neovascularization murine model
Molecular Medicine Reports
A pha r maceutical composition (patent no. WO2012079419) exhibited favorable outcomes in a clinical trial of wet age-related macular degeneration. The aims of the present study were to explore the effects of one composition component, charred Radix et Rhizoma Rhei (CRRR), in a laser-induced choroidal neovascularization (CNV) murine model. A total of 30 eight-week-old C57BL/6 mice were subjected to diode laser treatment, and CNV was induced by rupturing the Bruch's membrane. The mice were thendoi:10.3892/mmr.2014.3046 pmid:25482457 fatcat:palmwnc4rbhj7bn6offk6mqxvq