Spectrophotometric study of the interaction between arsenic and bovine serum albumin

Rolando Curvale, Nora Beatriz Debattista, Nora Beatriz Pappano, Diana Gonzalez, Daniela Alejandra Curvale
2015 Research and Reports in Biology  
Argentina is one of the countries that are most widely affected by chronic endemic regional hydroarsenicism, a syndrome caused by the constant consumption of water polluted with arsenic at higher levels. In this study, the interaction of bovine serum albumin with arsenite and arsenate was analyzed employing UV-Vis spectroscopy, considering its low cost and greater availability. The number of binding sites, binding constants, and thermodynamic parameters -∆G°, ∆H°, and ∆S° -were determined. The
more » ... esults obtained indicate that the interaction of bovine serum albumin with arsenate is ionic, while that with arsenite is hydrophobic.
doi:10.2147/rrb.s86486 fatcat:nwcoxdmpbfezlbcu7yp5hvipqe