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Decoyinine, an inhibitor of GMP synthetase, was used to induce sporulation under catabolite-repressed conditions in Bacilus subtilis. Sporulation-specific penicillin-binding proteins 4* and 5* were produced in abundance, and there was an increase in vegetative penicillin-binding proteins 2B and 3. These results, which were completely blocked by addition of guanosine, suggest that synthesis of penicillin-binding proteins is neither catabolite repressed nor directly dependent on the stringent response.doi:10.1128/jb.162.3.1302-1303.1985 fatcat:cxs57kmikfgnvlyror26ju2nty