Effect of Honey Supplementation on Clostridium Difficile Infection in Childhood Cancer

Mohsen Saleh El Alfy, Iman Ahmed Ragab, Sally Mohamed Saber
2018 The Egyptian Journal of Hospital Medicine  
the treatment of cancer is associated with nausea and vomiting, oral mucositis, constipation, xerostomia and diarrhea and weight loss, additionally; chemotherapeutic agents promote inflammatory changes in the gut, intestinal necrosis, and anaerobic conditions, allowing proliferation of Clostridium Difficile. Honey, as a natural honeybee product, has antioxidant, antimicrobial, immunomodulatory and anticancer effects. Honey can fight microbial infection by its immuno-activating,
more » ... and prebiotic activity. Objectives: the aim of this study was to evaluate the effect of honey supplementation on frequency of Clostridium Difficile infection (CDI) and gastrointestinal complications in pediatric patients undergoing chemotherapy. Design: a cross sectional study conducted on 40 patients with malignancy recruited from Children's Hospital,
doi:10.12816/0045662 fatcat:zoqhdow64zao5o2wdjuc5owany