STUDY OF CLINICAL AND LABORATORY PROFILE IN PATIENTS OF FEVER WITH THROMBOCYTOPENIA AND ITS OUTCOME DURING HOSPITAL STAY- A STUDY AT RIMS, A TERTIARY CARE HOSPITAL AT ONGOLE, PRAKASAM DISTRICT OF ANDHRA PRADESH
Journal of Evolution of Medical and Dental Sciences
BACKGROUND Fever with thrombocytopenia may manifest in infective and non-infective conditions. Thrombocytopenia is often missed, because it is not often looked for and the required investigations are not generally asked for. MATERIALS AND METHODS A hospital-based descriptive study conducted at Rajiv Gandhi Institute of Medical Sciences (RIMS), Ongole on 115 patients with fever associated with thrombocytopenia. Study duration was for one and a half years from January 2016 to June 2017. Data was
... une 2017. Data was collected using a semi-structured questionnaire, either by direct interview with patients or patient's relatives and by clinical examination and from relevant investigations. Patients were regularly monitored and depending on aetiological basis appropriate treatment was given. RESULTS Out of the 115 patients, dengue was the most common diagnosis found in the present study with 60% (n= 69) followed by unknown viral fevers (15.6%), then malaria (8.8%) and sepsis (6.1%). 5 cases were HIV positive, 3 cases had viral hepatitis and 3 enteric fever. Out of the total 69 dengue cases, 20 cases (28.9%) had platelet count in range of 40,001 -60,000. 17 cases had in range of 20,001 -40,000 and 15 dengue cases had severe thrombocytopenia (< 20,000). 110 cases (95.6%) showed good recovery, 2 patients expired, and 3 patients left against medical advice. CONCLUSION Febrile illness patients should be investigated for low platelet count whether they have bleeding manifestations or not. A routine CBC (complete blood count) investigation in all febrile illness cases will help to find its association with thrombocytopenia. KEY WORDS Fever, Thrombocytopenia, Clinical and Laboratory Profile, Outcome. HOW TO CITE THIS ARTICLE: Srinivas G, Rao YR. Study of clinical and laboratory profile in patients of fever with thrombocytopenia and its outcome during hospital stay-a study at RIMS, a tertiary care hospital at Ongole, Prakasam district of Andhra Pradesh.