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AbstractThe ghrelin–ghrelin receptor system is one of the most important mechanisms regulating energy balance and metabolism. Among other actions, central and peripheral administration of ghrelin increases food intake and adiposity. During the last years, many efforts have been made in the investigation of the cellular and molecular mechanisms modulating the effects of ghrelin. One particularity of this peptide hormone is its acylation at serine-3 with an eight-carbon fatty acid (octanoate),doi:10.1530/eje-10-0099 pmid:20421334 fatcat:x2ftubxnbrg5xfb43vrkz75tky