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Defense reactions of the dental pulp involve a variety of biological reactions, in which the immune system plays a very important role. The class II major histocompatibility complex (MHC) molecule expressing cells, termed dendritic cells and lymphocytes in human dental pulp are highly sensitive to exogenous antigenic stimuli. Their drastic changes in number and localization are induced by dental caries. This study investigated the responses of the immune system in two different clinicaldoi:10.33320/maced.pharm.bull.2015.61.02.004 fatcat:4xajyqg3ircltktrerbinh4pdu