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The role of the polarizing zone in the pattern of experimental chondrogenesis in the chick embryo interdigital space
1991
International Journal of Developmental Biology
We have previously shown that removal of the apical ectodermal ridge of the third interdigital space of the chick leg bud at stages 28 and 29 is followed by the appearance of ectopic cartilage, which in the course of development gives rise to extra digits. These in vivo studies suggest that the pattern of skeletal morphogenesis in the limb depends on the inhibitory effect of the ectoderm. In the present study we tested whether zone polarizing activity (ZPA) exerted an effect on the pattern of
pmid:1868002
fatcat:4srhqcxib5a2nkrbi3bj6smrdi