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Defective interferon amplification and impaired host responses against influenza virus in obese mice
2021
Obesity
Obesity is a major risk factor that increases morbidity and mortality upon infection. Although type I and type III interferon (IFN)-induced innate immune responses represent the first line of defense against viral infections, their functionality in the context of metabolic disorders remains largely obscure. This study aimed to investigate IFN responses upon respiratory viral infection in obese mice.
doi:10.1002/oby.23196
pmid:34314110
fatcat:gol6t7uxxjdu7latnz4jgfjuzy