The Evaluation of Estrogen Receptor β as a Potential Prognosis Factor in Melanoma

2020 Revista de chimie (Bucuresti)  
Differences across sexes in cutaneous melanoma incidence, metastatic pathways and disease outcome are consistently observed, with women having a significant survival advantage compared with men. This suggests that gender could play a role as a prognostic indicator through sex hormone signaling, but the mechanism is still unclear. This article focuses on available literature data concerning the influence of estrogen receptor beta (ERβ) expression as a host-related biological protective factor
more » ... rotective factor for female patients with melanoma. Furthermore, it highlights the potential role of estrogen receptor beta (ERβ) as a prognostic biologic marker in cutaneous melanoma. Keywords: melanoma, sex, hormone receptors, estrogen receptor β
doi:10.37358/rc.19.12.7734 fatcat:uztb5qnlw5fclfd4l63f7wvdne