The INDEX project (Critical Appraisal of the Setting and Implementation of Indoor Exposure Limits in the EU) Summary on recommendations and management options EUROPEAN COMMISSION 2 Funding: DG Consumer Protection (SANCO) and JRC/IHCP/PCE

Christian Cochet, Stylianos Kephalopoulos, J Matti, Jantunen, Thomas Lindvall, Prof Maroni, Luigi Sacco, James Mclaughlin, Lars Mølhave, Seifert Bernd, Abteilung Umweltbundesamt, Umwelthygiene
2004 unpublished
Foreword In the past decades a large number of studies have indicated the presence of various chemical compounds in indoor environments (buildings, homes). The presence of these chemicals in indoor air is the result of infiltration of polluted outdoor air and of emissions from various indoor sources, including building materials, activities of the occupants, consumer products, smoking etc. For many of these chemicals, the impact on human health and comfort is almost totally unknown and
more » ... nknown and difficult to predict because of the lack of toxicological data and of information on the dose-response characteristics in humans or animal models. On the other hand, a full toxicological testing as requested by the "existing chemicals" legislation is difficult to accomplish for these compounds, because it would involve the investigation of acute and sub-acute toxicity, mutagenicity, carcinogenicity and reproductive toxicity according to testing protocols that are complex, time-consuming and expensive. Moreover, the EU policy on limitation of unnecessary animal testing further limits the possibility of advocating a generalized animal testing of these chemicals. The result of this situation is that there is an objective difficulty in regulating the presence of chemicals in indoor air principally because of the absence of adequate hazard and risk assessment. There is therefore an urgent need to develop a strategy for the identification of priorities in testing, assessment and regulation. In the frame of the INDEX project the existing knowledge worldwide has been assessed on-type and levels of chemicals in indoor air and on-available toxicological information to allow the assessment the impact on health and comfort. The collection and evaluation of the aforementioned information within the frame of the INDEX project shall contribute to develop a strategy for prioritization in assessment and regulation of chemicals in indoor environments. The Steering Committee 3 Organisation responsible of the project: European Commission,