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Understanding the Human Brain using Brain Organoids and a Structure-Function Theory
[article]
2020
bioRxiv
pre-print
A basic neurobiology-clinical trial paradigm motivates our use of constrained mathematical models and analysis of personalized human-derived brain organoids toward predicting clinical outcomes and safely developing new therapeutics. Physical constraints imposed on the brain can guide the analyses an interpretation of experimental data and the construction of mathematical models that attempt to make sense of how the brain works and how cognitive functions emerge. Development of these
doi:10.1101/2020.07.28.225631
fatcat:3um4jycuzvap5cryq4rwkyufwu