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Mitochondrial Alteration: A Major Player in Carcinogenesis
2015
Cell Biology
In recent years we have witnessed mounting evidences on how a normal cell changes its cellular signaling and metabolic pathways to become highly proliferative cancer cell. Since mitochondrion is a major hub of energy production and several metabolic pathways, it is taking the center stage in defining alterations in energy homeostasis and metabolic rerouting of cancer cell proliferation. Similarly, mutations in the mitochondrial genome in cancer are providing new insights on how these mutations
doi:10.11648/j.cb.s.2015030201.12
fatcat:yoyldgoxsnerxl4n5yks6ymawa