Dietary Phytochemical Index and the Risk of Breast Cancer: A Case Control Study in a Population of Iranian Women

Zahra Bahadoran, Zeinab Karimi, Anahita Houshiar-Rad, Hamid-Reza Mirzayi, Bahram Rashidkhani
2013 Asian Pacific Journal of Cancer Prevention  
In this study we assessed the dietary phytochemical index in relation to the risk of breast cancer in women. This case-control study was conducted on 100 incident breast cancer cases and 175 healthy controls. Data regarding socio-demographic factors, medical history, medications, and anthropometric measurements were collected. Dietary data were obtained using a validated food frequency questionnaire and a energy-adjusted dietary phytochemical index (PI) was calculated. The odds ratios of breast
more » ... cancer were assessed across energyadjusted PI quartile categories. The mean age of participants was 46.2±8.9 and 45.9±9.4 years in cases and controls, respectively. The mean PI across quartile categories was 13.9±2.6, 21.1±1.8, 26.7±2.1, 41.6±10.2 in the first, second, third and fourth quartiles, respectively. After adjustment for all potential confounders, the risk of breast cancer in the forth quartile of dietary PI was significantly decreased (OR=0.08, 95%CI=0.01-0.84). Higher intake of phytochemical-rich foods is associated with lower risk of breast cancer.
doi:10.7314/apjcp.2013.14.5.2747 fatcat:p7t47xltrjbmzjjhr4upbi434y