Fine needle aspiration cytology of Gouty Tophi with review of literature

C Agarwal, A Harbhanjanka, K Agarwal, S Pahuja
2007 Journal of Cytology  
A fifty years old male presented with multiple subcutaneous nodules on both the lateral malleoli and medial border of left great toe ranging in size from 0.5-1.5 cm diameter (Fig 1) . These nodules were firm, mobile and non-tender. Patient had no systemic complaints. Radiographs of both the feet (anterior-posterior view) showed extensive soft tissue swellings overlying base of left great Case Report Abstract Fine needle aspiration cytology (FNAC) is a valuable diagnostic tool and is replacing
more » ... and is replacing biopsy for the diagnosis of periarticular nodules. We present a case of fifty year old male with multiple soft tissue nodules in feet without any clinical and radiological features of arthritis. Fine needle aspiration revealed negatively birefringent needle shaped crystals consistent with monosodium urate crystals in amorphous granular debris. Diagnosis of gouty tophi was given. On follow up serum uric acid levels were found to be high and a diagnosis of gout was established. FNAC is a valuable diagnostic tool for the diagnosis of periarticular nodules and pathologists should be aware of cytological features of gouty tophi, particularly in cases of unusual presentation.
doi:10.4103/0970-9371.41906 fatcat:32e5jlenwnh2hj6tfsnkncu4q4