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Magnetic resonance imaging (MRI) is commonly employed for the depiction of soft tissues, most notably the human brain. Computer-aided image analysis techniques lead to image enhancement and automatic detection of anatomical structures. However, the information contained in images does not often offer enough contrast to robustly obtain a good detection of all internal brain structures, not least the deep grey matter nuclei. We propose a method that incorporates prior anatomical knowledge in thedoi:10.15837/ijccc.2007.1.2333 fatcat:7c3zf7epqfba3lr6duln7goeaa