Abdominal obesity phenotypes outcomes: protocol for a systematic review [post]

Soraya Doustmohamdian, Farhad Hosseinpanah, Marjan Momeni
2020 unpublished
Background: The prevalence of obesity is increasing in the worldwide. Obesity is associated with serious health effects. Abdominal obesity has a stronger association with metabolic dysfunction.Methods: We will search PubMed/MEDLINE, EMBASE, Web of Science, Cochrane Library, and ProQuest (from inception onwards). Additional studies will be identified through manual searching of reference lists. Quantitative studies evaluating the abdominal obesity phenotypes outcomes in adult will be included.
more » ... will be included. Main outcomes will be assay the abdominal obesity phenotypes outcomes included risk of DM2, cardiovascular and all cause mortality. Two reviewers will independently screen full-text articles, and abstract data. Potential conflicts will be resolved through discussion. The study methodological quality (or bias) will be appraised using appropriate tools. If feasible, we will conduct random effects meta-analysis. The two researchers also will be assessed the quality of the articles independently based on CASP.Discussion: This systematic review will summarize the evidence regarding the association between abdominal obesity phenotypes and DM2, cardiovascular disease and all cause mortality. The results of this review will provide a useful reference for importance of abdominal obesity on metabolic dysfunction and mortality.Systematic review registration: International Prospective Register of Systematic Reviews PROSPERO.The protocol of the systematic review was drafted and uploaded to PROSPERO website. (PROSPERO CRD42019111056).
doi:10.21203/rs.3.rs-20631/v1 fatcat:tfvfjcbdsvh7tiiuucq4msvhou