Branched α-d-mannopyranosides: a new class of potent FimH antagonists

Tihomir Tomašić, Said Rabbani, Martina Gobec, Irena Mlinarič Raščan, Črtomir Podlipnik, Beat Ernst, Marko Anderluh
2014 MedChemComm  
We report branched α-d-mannopyranosides as potent FimH antagonists that exploit the previously unexplored lipophilic region formed by Phe142 and Ile13.
doi:10.1039/c4md00093e fatcat:m2mgtzf2cfewpfkhfqktlcbv5m