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Small Changes in Troponin T Levels Are Common in Patients With Non–ST-Segment Elevation Myocardial Infarction and Are Linked to Higher Mortality

Christian Bjurman, Mårten Larsson, Per Johanson, Max Petzold, Bertil Lindahl, Michael L.X. Fu, Ola Hammarsten
2013 Journal of the American College of Cardiology  

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Objectives The purpose of this study was to examine the extent of change in troponin T levels in patients with non-ST-segment elevation myocardial infarction (NSTEMI). Background Changes in cardiac troponin T (cTnT) levels are required for the diagnosis of NSTEMI, according to the new universal definition of acute myocardial infarction. A relative change of 20% to 230% and an absolute change of 7 to 9 ng/l have been suggested as cutoff points. Methods In a clinical setting, where a change in
more » ... T was not mandatory for the diagnosis of NSTEMI, serial samples of cTnT were measured with a high-sensitivity cTnT (hs-cTnT) assay, and 37 clinical parameters were evaluated in 1,178 patients with a final diagnosis of NSTEMI presenting <24 h after symptom onset.
doi:10.1016/j.jacc.2013.06.050 pmid:23933541 fatcat:ccfwkcpyzbafrf7hrp3z45ouue
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Christian Bjurman, Mårten Larsson, Per Johanson, Max Petzold, Bertil Lindahl, Michael L.X. Fu, Ola Hammarsten. "Small Changes in Troponin T Levels Are Common in Patients With Non–ST-Segment Elevation Myocardial Infarction and Are Linked to Higher Mortality." Journal of the American College of Cardiology 62.14 (2013) 1231-1238