A Label-free and Highly Sensitive Fluorescence Strategy for Mercury Ion Detection Based on Exonuclease III-aided Recycling Amplification

Baomiao DING, Chenguang LIU, Qinghua WU, Yun WANG, Li LI, Hualin YANG
2018 Analytical Sciences  
In this paper, we describe a simple and highly sensitive fluorescence strategy of mercury ions based on exonuclease III (Exo III)-aided target recycling amplification to ensure sensitivity. With an ultra high sensitivity (1 pM), our strategy has been simple and cost-effective, which does not need any artificial modification fluorescence groups, and can be carried out in a pot. It also shows excellent selectivity. Therefore, our new method provides an effective platform for mercuryion detection.
doi:10.2116/analsci.34.259 pmid:29526891 fatcat:igqlxsayurcwzijzybtlnjptwe