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Essentials for ATP Synthesis by F1F0ATP Synthases
2009
Annual Review of Biochemistry
The majority of cellular energy in the form of adenosine triphosphate (ATP) is synthesized by the ubiquitous F 1 F 0 ATP synthase. Power for ATP synthesis derives from an electrochemical proton (or Na + ) gradient, which drives rotation of membranous F 0 motor components. Efficient rotation not only requires a significant driving force ( μH + ), consisting of membrane potential ( ψ) and proton concentration gradient ( pH), but also a high proton concentration at the source P side. In vivo this
doi:10.1146/annurev.biochem.78.081307.104803
pmid:19489730
fatcat:5lhuzo735jhfzet22brycqz4qy