A Comparative Study between Levobupivacaine with Dexmedetomidine Versus Levobupivacaine with Clonidine in Ultrasound Guided Supraclavicular Brachial Plexus Block for Upper Limb Surgeries: A Randomized Double Blind Placebo Controlled Study ORIGINAL RESEARCH

Gopal Krishan, Subhro Mitra, A Verma, Malti Agrawal, Ram Singh, Sarfraj Ahmad
2018 International Journal of Contemporary Medical Research   unpublished
Brachial plexus block is more advantageous for routine as well as emergency upper limb surgery. This provides a useful alternative to general anesthesia for upper limb surgeries. Brachial plexus block provides very good intraoperative anesthesia as well as postoperative analgesia without any significant systemic side effects. This study was conducted to compare the perioperative analgesic efficacy of clonidine and dexmedetomidine for supraclavicular brachial plexus block along with
more » ... ne. Material and methods: A randomized double blind controlled study was done on 90 patients of ASA Grade I or II undergoing upper limb surgery. Group L-received levobupivacaine 0.5% (25ml) 125 mg and 1.0 ml normal saline, Group C-received levobupivacaine 0.5% (25ml) 125 mg and 1.0ml (150 microgram) clonidine and Group D-received levobupivacaine 0.5% (25ml) 125 mg and 1.0ml (100 microgram) dexmedetomidine. Onset and duration of both sensory and motor blockade and duration of analgesia were studied in all the three groups. Results: It was observed that in group D, onset of motor and sensory blockade was faster than group L and C. Significant difference was not observed in heart rate and blood pressure in any of the Groups. Group D had longer duration of analgesia in comparison of group C and group L. Conclusion: We concluded that dexmedetomidine added to levobupivacaine in supraclavicular brachial plexus block enhanced the duration of sensory and motor blockade and also the duration of analgesia.