The metamorphic malware variants with the same malicious behavior (family), can obfuscate themselves to look different from each other. This variation in structure leads to a huge signature database for traditional signature matching techniques to detect them. In order to effective and efficient detection of malware in large amounts of executables, we need to partition these files into groups which can identify their respective families. In addition, the grouping criteria should be chosen such

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... way that, it can also be applied to unknown files encounter on computers for classification. This paper discusses the study of malware and benign executables in groups to detect unknown malware with high accuracy. We studied sizes of malware generated by three popular second generation malware (metamorphic malware) creator kits viz. G2, PS-MPC and NGVCK, and observed that the size variation in any two generated malware from same kit is not much. Hence, we grouped the executables on the basis of malware sizes by using Optimal k-Means Clustering algorithm and used these obtained groups to select promising features for training (Random forest, J48, LMT, FT and NBT) classifiers to detect variants of malware or unknown malware. We find that detection of malware on the basis of their respected file sizes gives accuracy up to 99.11% from the classifiers.