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Biomarker Potential of Urine miR-451 at Different Stages of Diabetic Nephropathy

Emel Isiktas Sayilar
2016 Journal of Diabetes & Metabolism  

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Aims: To evaluate the potential of urinary miR-451 as a biomarker at different stages of diabetic nephropathy. Methods: A total of 45 subjects having stage 3 chronic kidney disease (n=15) or stage 5 chronic kidney disease (n=15) and 15 healthy volunteers were included. Data on patient demographics, laboratory findings [creatinine, estimated glomerular filtration rate, urinary protein excretion] target genes and functions of the selected MicroRNAs associated with diabetic nephropathy and fold
more » ... ferences in the level of MicroRNA expression in blood and urine and the correlation of urine and plasma MicroRNA expression with estimated glomerular filtration rate were recorded.
doi:10.4172/2155-6156.1000650 fatcat:yemyoygtarezfbbtuapnxpme3a
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Emel Isiktas Sayilar. "Biomarker Potential of Urine miR-451 at Different Stages of Diabetic Nephropathy." Journal of Diabetes & Metabolism 07.02 (2016)