Corticostriatal Interactions during Learning, Memory Processing, and Decision Making

C. M. A. Pennartz, J. D. Berke, A. M. Graybiel, R. Ito, C. S. Lansink, M. van der Meer, A. D. Redish, K. S. Smith, P. Voorn
2009 Journal of Neuroscience  
This mini-symposium aims to integrate recent insights from anatomy, behavior, and neurophysiology, highlighting the anatomical organization, behavioral significance, and information-processing mechanisms of corticostriatal interactions. In this summary of topics, which is not meant to provide a comprehensive survey, we will first review the anatomy of corticostriatal circuits, comparing different ways by which "loops" of cortical-basal ganglia circuits communicate. Next, we will address the
more » ... al importance and systems-neurophysiological mechanisms of corticostriatal interactions for memory, emphasizing the communication between hippocampus and ventral striatum during contextual conditioning. Furthermore, ensemble recording techniques have been applied to compare information processing in the dorsal and ventral striatum to predictions from reinforcement learning theory. We will next discuss how neural activity develops in corticostriatal areas when habits are learned. Finally, we will evaluate the role of GABAergic interneurons in dynamically transforming cortical inputs into striatal output during learning and decision making.
doi:10.1523/jneurosci.3177-09.2009 pmid:19828796 pmcid:PMC3849625 fatcat:icvztddxrnbfzl5jqh5r4thsua