A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf
.
Quality control issues and the identification of rare functional variants with next-generation sequencing data
2011
Genetic Epidemiology
Next-generation sequencing of large numbers of individuals presents challenges in data preparation, quality control, and statistical analysis because of the rarity of the variants. The Genetic Analysis Workshop 17 (GAW17) data provide an opportunity to survey existing methods and compare these methods with novel ones. Specifically, the GAW17 Group 2 contributors investigate existing and newly proposed methods and study design strategies to identify rare variants, predict functional variants,
doi:10.1002/gepi.20645
pmid:22128054
pmcid:PMC3268158
fatcat:l4um6tlbofcadic2lyizdhvmya