Untersuchungen zur Synthese von Baccatinen in Zellkulturen von Corylus avellana L

Elisabeth Schatzl
2012 unpublished
Paclitaxel (trade name Taxol) has been originally isolated from the pacific yew, Taxus brevifolia Nutt.. Taxol is a proven cytostatic drug. In the search of novel sources of taxanes these compounds were also found in extracts of the hazel cultivar Corylus avellana cv. "Gasaway". The taxane content of hazelnut can be influenced by elicitation. A total of three abiotic elicitations were carried out to influence taxane formation with sucrose, silver nitrate and ammonium citrate. It could be shown
more » ... hat it is generally possible to influence taxane formation in the investigated hazel cell line.
doi:10.25365/thesis.23574 fatcat:es223nelxza5beeknulghygty4