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Drug side-effects are crucial issues in both the premarket drug developing process and post-market drug clinical applications. They contribute to one-third of drug failures and cause significant fatality and severe morbidity. Thus the early identification of potential drug sideeffects is of great interests. Most existing methods essentially rely on leveraging few drug similarities directly for side-effect predictions, ignoring the performance improvement by drug similarity integration anddoi:10.22489/cinc.2017.128-068 dblp:conf/cinc/ZhengGL17 fatcat:zvb34dfurbgm7nurjyonwxh7e4