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Data relating to cancer treatment in the older patient population are limited because older individuals have been under-represented in clinical trials. The goal of this review was to establish which factors hinder the participation of older individuals to clinical trials and to examine possible solutions. Methods: The literature relating to cancer treatment in the older patient population was reviewed. Results: The benefit of systemic cancer treatment may decrease with age, and risks may bedoi:10.1177/107327481402100306 pmid:24955705 fatcat:emgzypchuzhqrl35owndszixpm