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Earlier injection and inhalation studies with uranium trioxide (UO,) indicated that the material was more similar to soluble uranyl salts than to the so-called insoluble oxides, U,Os and UO" but quantitative data were lacking. This inhalation study of UO, (enriched with 235U) in dogs substantiated the earlier studies with the findings that (a) UO, is rapidly removed from the lungs, with most following a 4.7 day biological half time; (b) systemic absorption amounted to more than 20% of thedoi:10.1097/00004032-197209000-00001 pmid:4642950 fatcat:prlygxwrevanrnijdvxy75krge