誗 AIM: To compare and analyze the clinical treatment effect of primary pterygium with amniotic membrane transplantation, autologous corneal limbus stem cell transplantation and intraoperative application of 0. 2g / L mitomycin C. 誗METHODS: Retrospective analysis of 232 patients who were underwent primary pterygium surgery was performed. Eighty-two cases were treated with amniotic membrane transplantation, 90 with autologous corneal limbus stem cell transplantation, and 60 with intraoperative

more »

... lication of 0. 2g / L mitomycin C. The postoperative recurrence and complications of three operative methods were compared. 誗 RESULTS: The recurrence rate of autologous corneal limbus stem cell transplantation and intraoperative application of 0. 2g / L mitomycin C was lower than that of amniotic membrane transplantation (P < 0. 05). The recurrence rate between autologous corneal limbus stem cell transplantation and intraoperative application of 0. 2g / L mitomycin C had no difference (P > 0. 05). Corneal epithelium defect, tears and photophobia were higher in 0. 2g / L mitomycin C group (P < 0. 05) , which were no statistical difference between autologous corneal limbus stem cell transplantation and amniotic membrane transplantation (P > 0. 05). Conjunctival congestion and subconjunctival hemorrhage in three groups had no statistical difference (P>0. 05). 誗 CONCLUSION: Compared with other two operative methods, autologous corneal limbus stem cell transplantation for primary pterygium has the advantages of lower recurrence rate and less complications. 誗 KEYWORDS: pterygium; amniotic membrane transplantation; autologous corneal limbus stem cell transplantation; mitomycin C Citation: Zhang Y, Kong LP, Wang C, et al. Clinical effect analysis of different surgical treatment of primary pterygium. Guoji Yanke Zazhi(Int Eye Sci) 2015;15(2) :361-363 摘要 目的:比较分析羊膜移植术、自体角膜缘干细胞移植术及 术中应用 0. 2g / L 丝裂霉素 C 治疗原发性翼状胬肉的临床 效果。 方法:回顾性分析我院 232 例曾行原发性翼状胬肉手术的 患者,其中 82 例行羊膜移植术治疗,90 例行自体角膜缘 干细胞移植术治疗,60 例在术中应用 0. 2g / L 丝裂霉素 C 治疗,比较三种术式术后复发率及并发症。 结果:自体角膜缘干细胞移植术和术中应用 0. 2g / L 丝裂 霉素 C 治疗原发性翼状胬肉的复发率低于羊膜移植术(P< 0郾 05) ;而自体角膜缘干细胞移植术和术中应用 0. 2g / L 丝 裂霉素 C 之间复发率无差异(P>0. 05) 。 角膜上皮缺损, 流泪和畏光在 0. 2g / L 丝裂霉素组发生比例较其他两组高 (P<0. 05) ,在自体角膜缘干细胞移植组和羊膜移植组两 组间差异无统计学意义(P>0. 05) 。 结膜充血及结膜下出 血在三组间无统计学差异(P>0. 05) 。