IS FROZEN SECTION OBSOLETE
Journal of Evidence Based Medicine and Healthcare
Frozen section enjoys popularity among surgeons worldwide, as a preoperative investigation and is preferred over paraffin sections because of its less time consuming nature, cost-effectiveness and for immuno histochemistry. If through inspection of the specimen and selection of the most suspicious area during examination. Taking more than one sample would make frozen section diagnosis more accurate. Avoid areas of necrosis, hemorrhage, calcification, cystic areas and highly friable tissues
... riable tissues prior fixation because they lead to technically poor preparation of slides and more probable sources of errors. DISCUSSION: Thyroid lesions are the most common endocrine lesions. Study was conducted with interest and because of well-established Cryostat frozen section technique. According to Ackerman et al (8) and Fazilet et al, (9) a definitive diagnosis of thyroid lesions by frozen sections was possible in a high percentage of instances. Sensitivity was 94.29%, specificity 100%, positive predictive value 100% and negative predictive value was 99%. CONCLUSION: Thyroid disease prevalence made the surgical requirement for urgent intraoperative diagnosis. There is always a danger of unnecessary thyroidectomy with false positive clinical and cytological diagnosis. Therefore intra-operative cryostat section diagnosis is recommended as routine method for management of thyroid lesions. Periodic survey of cryostat sections diagnosis should be an integral part of the quality assurance programme and educate both pathologist and surgeons to improve the management which is the ultimate goal.