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Step-scan Fourier Transform Inflared (FT-IR) Photoacoustic Spectroscopy (PAS) has been used to study the penetration of substances through abdominal pig skin. The experiments were performed in vitro and dimethylsulfoxide(DMS0) was applied either onto the surface or the bottom of the sample. The results demonstrated that DMSO propagated fast through the skin from the bottom sur$ace. The ease of identijication of this substance in this spectral range showed the potential of the technique,doi:10.1051/jp4:19947104 fatcat:fc2dtnc235bzze3axia2o7nv3i