Fourier transform infrared photoacoustic spectroscopy to study the penetration of substances through skin

M. L. Baesso, R. D. Snook, J. J. Andrew
1994 Journal de Physique IV : Proceedings  
Step-scan Fourier Transform Inflared (FT-IR) Photoacoustic Spectroscopy (PAS) has been used to study the penetration of substances through abdominal pig skin. The experiments were performed in vitro and dimethylsulfoxide(DMS0) was applied either onto the surface or the bottom of the sample. The results demonstrated that DMSO propagated fast through the skin from the bottom sur$ace. The ease of identijication of this substance in this spectral range showed the potential of the technique,
more » ... technique, suggesting that penetration and distribution of other chemicals through the skin can be investigated by FT-IR PAS.
doi:10.1051/jp4:19947104 fatcat:fc2dtnc235bzze3axia2o7nv3i