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Lecture Notes in Computer Science
A current major challenge in systems biology is to compute statistics on biomolecular network motifs, since this can reveal significant systemic differences between organisms. We extend the "color coding" technique to weighted edge networks and apply it to PPI networks where edges are weighted by probabilistic confidence scores, as provided by the STRING database. This is a substantial improvement over the previously available studies on, still heavily noisy, binary-edge-weight data. Followingdoi:10.1007/978-3-642-04241-6_4 fatcat:hgna3xph75dbriowohshroemfu