Wide-field absolute transverse blood flow velocity mapping in vessel centerline

Nanshou Wu, Lei Wang, Bifeng Zhu, Caizhong Guan, Mingyi Wang, Dingan Han, Haishu Tan, Yaguang Zeng
2018 Journal of Biomedical Optics  
Wide-field absolute transverse blood flow velocity mapping in vessel centerline," J. Abstract. We propose a wide-field absolute transverse blood flow velocity measurement method in vessel centerline based on absorption intensity fluctuation modulation effect. The difference between the light absorption capacities of red blood cells and background tissue under low-coherence illumination is utilized to realize the instantaneous and average wide-field optical angiography images. The absolute fuzzy
more » ... connection algorithm is used for vessel centerline extraction from the average wide-field optical angiography. The absolute transverse velocity in the vessel centerline is then measured by a cross-correlation analysis according to instantaneous modulation depth signal. The proposed method promises to contribute to the treatment of diseases, such as those related to anemia or thrombosis.
doi:10.1117/1.jbo.23.2.026008 pmid:29488364 fatcat:o43um2e3ybfrbppfxzxqxab6x4