Two fundamental laws are needed for prediction in the universe: (1) a basic dynamical law and (2) a law for the cosmological initial condition. Quantum cosmology is the area of basic research concerned with the search for a theory of the initial cosmological state. The issues involved in this search are presented in the form of eight problems. * * * IGUSes are complex adaptive systems in the context of quantum mechanics. For more on the general characterization of complex adaptive systems see [16] .