Antioxidant and antimicrobial activities of the extracts of the Calyx of Hibiscus Sabdariffa Linn

John Mensah, Divine Golomeke
2015 Calyx of Hibiscus Sabdariffa Linn. Current Science Perspectives   unpublished
The calyces of Hibiscus sabdariffa Linn are widely used for nutritional and medicinal purposes in Ghana. This study assessed the antioxidant and antimicrobial activities of the aqueous and the ethanol (hydro-ethanol) extracts (30%) of the calyces of H. sabdariffa Linn. The hydro-ethanol extract exhibited a more potent antioxidant potential versus aqueous extract as demonstrated by its higher Total Antioxidant Capacity (TAC) and its lower EC 50 for both the DPPH and the Hydroxyl radical
more » ... g activities. Additionally, the hydro-ethanolic extract displayed more potent antimicrobial activities with larger zones of inhibition in the agar diffusion assay and lower MICs in the broth dilution assay against a set of microorganisms including Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis and Candida albicans. The data supports the ethnomedicinal use of the aqueous infusion of H. sabdariffa Linn for the management of urinary tract infections and other symptoms that may be linked to oxidative stress. Capsule Summary: The antioxidant and antimicrobial activities of the aqueous and ethanol (hydro-ethanol) of Hibiscus sabdariffa were assessed. Results showed that hydro-ethanol extracts showed higher antioxidant activity in terms of TAC, EC50 and DPPH as well as antimicrobial activity against set of microbes.
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