Rheology of Giant Vesicles: A Micropipette Study

N. Fa, C. M. Marques, E. Mendes, A. P. Schröder
2004 Physical Review Letters  
We develop a micropipette rheometer to study the effect of oscillatory shear flow on the spontaneous fluctuations of phospholipid bilayers. Our results on giant vesicles show that oscillatory shear flow leads to a suppression of membrane fluctuations. They also imply that the Helfrich equation is modified in the presence of the flow. This equation, a fundamental constitutive relation between the amount of area stored in the fluctuations and the membrane tension, must be supplemented under
more » ... emented under oscillatory shear by a flow excess function that we determine.
doi:10.1103/physrevlett.92.108103 pmid:15089249 fatcat:npnmjv5wmnglrpkyrkoohrvzey