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Jugular bulb oxyhaemoglobin desaturation (SjO 2 ≤ 50%) during the rewarming phase of cardiopulmonary bypass (CPB) is associated with postoperative cognitive deficits . Isoflurane effects cerebral blood flow and cerebral metabolic rate, both of which affect SjO 2 . We report the effect of isoflurane on the incidence of desaturation during rewarming from CPB for coronary artery surgery. Introduction: Bleeding is of major concern in neonates after cardiopulmonary bypass. More severedoi:10.1186/cc654 fatcat:hu7j4r442vgbxhe2eqwtyesbkm