Seasonality of Respiratory Syncytial Virus - Lower Respiratory Tract Infection (RSV-LRTI) in Children in Developing Countries

Sirintip Sricharoenchai
2016 Journal of Human Virology & Retrovirology  
Respiratory Syncytial Virus (RSV), an enveloped RNA virus with a non-segmented single-stranded negative-sense genome, is the primary cause of hospitalization in the first year of life for children in most parts of the world. The global estimate in 2005 indicated that at least 33.8 million episodes of RSV associated acute lower respiratory infection (ALRI) occurred worldwide in children younger than 5 years and most of these deaths occurred in developing countries. This study aimed to
more » ... lly aggregate and analyze published epidemiological data on the seasonality of RSV lower respiratory tract infections in young children in developing countries. Articles in English published between 2002 and 2014 were identified through literature searches in PubMed, Web of knowledge, and Embase. The season in which RSV epidemics occur typically depends on geographical location and altitude. It is likely that several factors interact in complex ways in the development of epidemics under favorable climatic conditions.
doi:10.15406/jhvrv.2015.02.00076 fatcat:oorqvfq57zasvgkvkyhajg46hm