Múltiples úlceras perianales en relación al uso de una pomada hemorroidal con acetónido de triamcinolona, lidocaína y pentosano polisulfato sódico como principios activos: una serie de 11 pacientes españoles

D. Marín-Piñero, M. Iglesias-Sancho, J. Company-Quiroga, C. Martínez-Moran, P. Perez-Feal, I. Vazquez-Osorio, P. Rodriguez-Jiménez, J. Sánchez-Estella, A. Suárez-Valle, L. Buzón-Martín, E. Martín-Saez, S. García-Rodiño (+4 others)
2021 Actas Dermo-Sifiliográficas  
The development of perianal ulcers related to the use of a hemorrhoidal ointment has not been reported in the literature. We describe a series of 11 patients who were treated for perianal ulcers in 10 Spanish hospitals after they used the same ointment containing the active ingredients triamcinolone acetonide, lidocaine, and pentosan polysulfate sodium. No prior or concomitant conditions suggesting an alternative cause for the condition could be identified, and after the patients stopped using
more » ... he ointment, their ulcers cleared completely in 8 weeks on average. This case series shows the damage that can be caused by an over-the-counter pharmaceutical product used without medical follow-up. It also illustrates the need to ask patients with perianal ulcers about any topical agents used before the lesions appeared.
doi:10.1016/j.ad.2021.02.002 pmid:33636161 fatcat:l2ovtikmdrcrlk2sqdj7tbknb4