Glucocorticoid and mitogen sensitivity of rat splenic and thymic lymphocytes in vitro after in vivo cyclophosphamide treatment

S F Burroughs, J A Cidlowski
1978 Cancer Research  
that may arise as a result of combined therapy have not yet been fully researched and understood. This study examines the sensitivity of splenic and thymic lymphocytes to gluco corticoids and mitogens in vitro following in vivo treatment of animals with CY. CY is used in immunosuppression as well as cancer therapy (6) . It has found application particu larly for acute and chronic lymphocytic leukemia, multiple [3H]triamcinolone acetonide; TCA, trichloroacetic acid; B-cell, bone marrow derived
more » ... ne marrow derived lymphocytes; T-cell, thymus lymphocytes.
pmid:309791 fatcat:ujyhh6uisnb2xphhqyw2itolji