Dexoyribonucleic acid (DNA) has recently been identified as a promising material for nanotechnology due to its unique mechanical, electrical, and optical properties. However, optical applications are severely hampered by the featureless response of neutral DNA at visible frequencies. Additionally, predictive simulations are computationally too demanding to cope with large DNA strands. Here, we develop a computationally efficient procedure to simulate the optical response of large DNA molecules

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... nd reveal the emergence of electrically-tunable intense resonances in the visible spectral range. Our results support the potential of DNA for optoelectronics and biosensing applications.