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Stroma-Providing Activity Of Adipose Derived Mesenchymal Stromal Cells In Tissue-Related O2 Microenvironment
2014
Zenodo
This work studied the ability of adipose tissue-derived mesenchymal stromal cells (MSCs) to form stroma for expansion of cord blood hematopoietic cells. We showed that 72-hour interaction of MSCs with cord blood mononuclear cells (MNCs) in vitro at atmospheric (20%) and low (5%) O2 conditions increased the expression of ICAM-1, HCAM (at the beginning of interaction) on MSCs. Viability of MSCs and MNCs were maintained at high level. Adhesion of MNCs to MSCs was faster at 20% O2. MSCs promoted
doi:10.5281/zenodo.1094734
fatcat:wmhyaon64vhftj4atvqwpo3k7e