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Si-Miao-Yong-An Decoction maintains the cardiac function and protects cardiomyocytes from myocardial ischemia and reperfusion injury
[post]
2021
unpublished
Objective :The aim of this study was to determine whether Si-Miao-Yong-An decoction (SMYAD) could protect cardiomyocytes from ischemia/reperfusion (I/R) injury and its underlying mechanisms. Methods: C57BL/6 mice were used to establish a model of myocardial infarction by I/R injury and treated by SMYAD for 4 weeks. Then the cardiac functions of mice were evaluated by Cardiac Magnetic Resonance (CMR). Histopathological analysis for the heart remodeling was detected by H&E and Masson staining.
doi:10.21203/rs.3.rs-476965/v1
fatcat:5gbc3fp7bzb2zb2pyv7opx5ojq