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The Role of Attractin in Neurodegeneration Caused by Oxidative Stress
[chapter]
2016
Free Radicals and Diseases
Oxidative stress is linked to dopaminergic (DA) neurodegeneration in Parkinson's disease. Our laboratory reported slowly progressive DA neurodegeneration in the zitter (zi) rat, which is Attractin (Atrn) deficient. However, little is known about the function of Atrn in the central nervous system (CNS). Thus, we investigated whether DA neurodegeneration in the zi rat was induced by oxidative stress, and how Atrn affects oxidative stress. First, we summarize our previous in vivo data, which
doi:10.5772/63330
fatcat:ao7i2pwdrfgr5kt7q3cwmo2lv4