Improved data acquisition system for brain PET using GAPD arrays

Wei Hu, Yong Choi, Key Jo Hong, Jihoon Kang, Youn Suk Huh, Hyun Keong Lim, Sang Su Kim, Ji Woong Jung, Kyu Bom Kim, Byung-Tae Kim
2010 IEEE Nuclear Science Symposuim & Medical Imaging Conference  
We have previously reported that a brain PET using GAPD arrays was successfully developed. The brain PET consisted of 72 4 x 4 GAPD arrays combined with LYSO crystals (single pixel size: 3 mm x 3 mm). Each 4 GAPD arrays' output signals were sent to a 64:1 position decoder circuit (PDC) which detects the fastest gamma signal of 64 input channels. To further improve the PET system performance, several modifications were performed on the DAQ system: PET data from 3 DAQ cards were transferred and
more » ... ved on one SDRAM module by rapid channel communication; parallel processing and multiplexing based FPGA algorithm was developed to detect true PET signals by real time; a more user-friendly GUI DAQ control program was developed to control 3 DAQ cards simultaneously; an accurate and fast coincidence sorting method containing 3 discrimination approaches (time, energy and line of response discriminations) was developed to improve image quality. To evaluate the improved DAQ system, several experiments were performed such as sensitivity measurement using a 25 µ µ µ µci Na-22 point source, spatial resolution measurement using ten F-18 line sources with different source-to-center distances (-8 cm, -6 cm, -4 cm, -2 cm, 0, 2 cm, 4 cm, 6 cm, 8 cm and 10 cm), PET images acquisition of hot rod phantom and Hoffman brain phantom. Experimental results showed that PET sensitivity of 2594 cps/ MBq at 30% energy window (350-650 kev) was achieved. Spatial resolution from 2.9 mm (center) to 5 mm (25 cm off-center) was acquired for ten different source-to-center distances. PET images of hot rod phantom and Hoffman brain phantom were successfully acquired with improved image quality. The DAQ system developed in this study allows to acquiring high quality PET images using GAPD arrays.
doi:10.1109/nssmic.2010.5874426 fatcat:g4z4st3xurczbmqzhbf67rne6i