MATERNAL MEASLES ANTIBODY LEVELS AMONG SOUTH INDIAN INFANTS LESS THAN 9 MONTHS OF AGE – A CROSS – SECTIONAL STUDY
English

Sivagamasundari Venugopal, Rajesh Nagaraj Thangaraj, John Matthai
2016 Journal of Evidence Based Medicine and Healthcare  
BACKGROUND Infants are protected against measles infection by passive transfer of maternal anti-measles antibodies. Studies from the West have shown a steady decline in these antibody titers over increasing age. AIM This study is aimed to determine the maternal measles antibody titers (MMAT) at various ages in infants below nine months of age. MATERIALS AND METHODS Cord blood of thirty babies consecutively born at term and peripheral blood of 24, 27 and 36 infants at 4, 6 and 9 months of age
more » ... 9 months of age respectively were assayed for MMAT using standardised lab methods. RESULTS Eighty three percent of babies at term had MMAT in the protective range. But subsequently there is a steady decline in MMAT and none of the infants in the study had protective levels of MMAT at 9 months of age. CONCLUSION With such rapid decline in MMAT during infancy, the position of measles vaccine at nine months in national immunisation schedule needs to be revisited. KEYWORDS Measles, Measles antibody titres. HOW TO CITE THIS ARTICLE: Venugopal S, Thangaraj RN, Matthai J. Maternal measles antibody levels among South Indian infants less than 9 months of age -a cross -sectional study.
doi:10.18410/jebmh/2016/275 fatcat:5v7mrdtbcrgb3kwhccka7g7fya