Alteration in serum levels of copper, iron, zinc, vitamin C and lipid profile in patients with oral cancer and oral sub-mucous fibrosis

Arpit Vashistha, Manpreet Singh, Manoj Chaudhary, Gagandeep Kaur
2015 Journal of Chemical and Pharmaceutical Research   unpublished
In human race the most prevalent oro-dental diseases include; dental caries, pulpal and peri-apical inflammation, periodontal problems and many more conditions. Among these conditions cancer of the oral cavity in India has the uncertainly peculiarity among the world. Cancer of the oral cavity secures first rank among all cancers in male patients in India. Globally, Cancer of the oral cavity is 3 rd most common cancer in males and 4 th in females. Timely recognition of oral cancers and
more » ... s improves quality of life for affected patients. Aim of this study is to evaluate Serum levels of lipids, copper, iron, Zinc, vitamin C in patients with oral Cancer (Squamous cell carcinoma) and oral sub-mucous fibrosis (OSMF) associated with habit of tobacco consumption in any form and its comparison patients with oral habit of tobacco consumption in any form but without any lesion and with the patients among control group i.e. without any habit / lesion and in the patients having habit of tobacco but no lesion. After obtaining ethical clearance from the Institution and informed written consent from participants, 30 individuals with physical status ASA I and ASA II are included in this study. It can be concluded from the present study that levels of trace elements and lipids could be used as a prospective prognostic and diagnostic markers in patients with oral cancer / pre-cancerous lesions.